Achim Schmidtko Selected Research

Loxapine (Loxitane)

1/2019	Loxapine for Treatment of Patients With Refractory, Chemotherapy-Induced Neuropathic Pain: A Prematurely Terminated Pilot Study Showing Efficacy But Limited Tolerability.
1/2015	Slack channels expressed in sensory neurons control neuropathic pain in mice.

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Achim Schmidtko Research Topics

Disease

33	Pain (Aches) 06/2022 - 04/2003
19	Neuralgia (Stump Neuralgia) 06/2022 - 08/2008
16	Hyperalgesia 10/2021 - 10/2002
9	Hypersensitivity (Allergy) 10/2021 - 12/2009
8	Inflammation (Inflammations) 01/2020 - 03/2004
6	Chronic Pain 03/2019 - 05/2010
5	Peripheral Nerve Injuries 10/2014 - 01/2011
2	Neoplasms (Cancer) 12/2017 - 04/2003
1	Fibrosis (Cirrhosis) 01/2020
1	Communicable Diseases (Infectious Diseases) 01/2020
1	Malaria 01/2020
1	Abdominal Pain (Pain, Abdominal) 01/2019
1	Peritonitis 01/2019
1	Polyneuropathies (Polyneuropathy) 01/2019
1	Nausea 12/2009
1	Dizziness (Lightheadedness) 12/2009
1	Fatigue 12/2009

Drug/Important Bio-Agent (IBA)

8	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2022 - 01/2011
7	ZymosanIBA 01/2012 - 03/2004
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2004
6	Formaldehyde (Formol)FDA Link 09/2011 - 03/2003
5	Analgesics (Analgesic Drugs)IBA 01/2021 - 12/2009
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2019 - 08/2008
3	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 06/2022 - 03/2013
3	Pharmaceutical PreparationsIBA 12/2017 - 07/2004
3	AntioxidantsIBA 12/2013 - 01/2011
3	Cyclic GMP-Dependent Protein Kinase Type IIBA 08/2008 - 03/2004
2	Protein Isoforms (Isoforms)IBA 06/2022 - 03/2019
2	Superoxides (Superoxide)IBA 06/2022 - 03/2013
2	NADPH Oxidases (NAD(P)H oxidase)IBA 06/2022 - 03/2013
2	Potassium Channels (Potassium Channel)IBA 01/2022 - 01/2019
2	Capsaicin (Zostrix)FDA Link 01/2022 - 01/2022
2	Opioid Analgesics (Opioids)IBA 10/2021 - 04/2003
2	Pregabalin (Lyrica)FDA Link 01/2021 - 12/2009
2	Cysteine (L-Cysteine)FDA Link 01/2020 - 02/2008
2	Monomeric GTP-Binding ProteinsIBA 01/2020 - 01/2017
2	Loxapine (Loxitane)FDA LinkGeneric 01/2019 - 01/2015
2	EnzymesIBA 10/2015 - 03/2013
2	Guanosine Monophosphate (5' Guanylic Acid)IBA 10/2014 - 08/2014
2	Messenger RNA (mRNA)IBA 12/2013 - 09/2011
2	Protein Kinases (Protein Kinase)IBA 09/2011 - 03/2003
2	Synapsins (Synapsin I)IBA 10/2008 - 05/2005
2	Glutamic Acid (Glutamate)FDA Link 10/2008 - 05/2005
2	NF-kappa B (NF-kB)IBA 03/2007 - 02/2007
1	allyl isothiocyanateIBA 01/2022
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2022
1	CalciumIBA 10/2021
1	capadenosonIBA 01/2021
1	NADPH Oxidase 4IBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2021
1	Adenosine A1 ReceptorIBA 01/2021
1	Epoxide HydrolasesIBA 01/2020
1	LigandsIBA 01/2020
1	Serine (L-Serine)FDA Link 01/2020
1	NucleotidesIBA 01/2020
1	Soluble Guanylyl CyclaseIBA 03/2019
1	Dopamine (Intropin)FDA LinkGeneric 01/2019
1	narciclasineIBA 01/2019
1	CytokinesIBA 01/2019
1	Histamine Receptors (Histamine Receptor)IBA 01/2019
1	Antipsychotic Agents (Antipsychotics)IBA 01/2019
1	Intermediate-Conductance Calcium-Activated Potassium ChannelsIBA 10/2017
1	ProteomeIBA 01/2017
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 10/2015
1	CystathionineIBA 10/2015
1	LyasesIBA 10/2015
1	Oxidants (Oxidizing Agents)IBA 10/2014
1	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 10/2014
1	N,N''- 1,4- butanediylbis(N'- (3- isothiocyanatophenyl))thioureaIBA 09/2014
1	purinoceptor P2Y6IBA 09/2014
1	Purinergic Receptors (Receptors, Purine)IBA 09/2014
1	2- (3,4- dimethoxybenzyl)- 7- (1- (1- hydroxyethyl)- 4- phenylbutyl)- 5- methylimidazo(5,1- f)(1,2,4)triazin- 4 (3H)-oneIBA 08/2014
1	Cyclic NucleotidesIBA 08/2014
1	Type 2 Cyclic Nucleotide PhosphodiesterasesIBA 08/2014
1	Adenosine Monophosphate (AMP)IBA 08/2014
1	NS 1619IBA 03/2014
1	Activating Transcription Factor 3IBA 12/2013
1	tert-ButylhydroperoxideIBA 12/2013
1	NADP (NADPH)IBA 07/2012
1	Tamoxifen FDA LinkGeneric 07/2012
1	5,6-epoxy-8,11,14-eicosatrienoic acidIBA 05/2012
1	Glycine Receptors (Glycine Receptor)IBA 01/2012
1	VitaminsIBA 01/2011
1	Vitamin E FDA LinkGeneric 01/2011
1	Freund's AdjuvantIBA 01/2011
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2011
1	Peptides (Polypeptides)IBA 05/2010
1	ziconotide (Prialt)FDA Link 05/2010
1	Neurotransmitter Agents (Neurotransmitter)IBA 05/2010
1	N-Type Calcium Channels (N-Type Calcium Channel)IBA 05/2010
1	Ibuprofen (Motrin)FDA LinkGeneric 12/2009
1	Tramadol (K315)FDA LinkGeneric 12/2009
1	Menthol FDA Link 12/2009
1	ProstaglandinsIBA 04/2009
1	Prostaglandins DIBA 04/2009
1	Prostaglandins EIBA 04/2009

Therapy/Procedure

3	Spinal Injections 08/2014 - 01/2011
1	Intraperitoneal Injections 01/2021
1	Drug Therapy (Chemotherapy) 01/2019
1	Therapeutics 01/2019